| Item Name | Mega Demondrug (鬼人薬グレート) |
| Max Carry | 5 |
| Buy Price | 0z |
| Sell Price | 283z |
| Rarity | 5 |
| How to Get | Combine |
| Description | Increase attack points by 7, till the hunter done for. |
| First Item | Second Item | Item Result | Chance | Qty Result |
| Demondrug (鬼人薬) | Pale Extract (アルビノエキス) | Mega Demondrug (鬼人薬グレート) | 55% | 1 |
| Mega Demondrug (鬼人薬グレート) | Monster Bone M (竜骨【中】) | Demon Horn (鬼人笛) | 55% | 1 |
| Weapon Type | Production | Weapon Name | Require |
| Great Sword | Create | Valkyrie Blade (ヴァルキリーブレイド) | 2 |
| Upgrade | Finblade (フィンブレイド) | 1 | |
| Long Sword | Create | Diapason (ディアパゾン) | 3 |
| Upgrade | Plesioth Splasher (ガノスラッシャー) | 1 | |
| Upgrade | Diapason (ディアパゾン) | 3 | |
| Gun Lance | Create | Marine Fisher (マリンフィッシャー) | 2 |
| Upgrade | Marine Fisher (マリンフィッシャー) | 1 | |
| Hammer | Upgrade | Carapace Hammer+ (ドラグロハンマー改) | 1 |